Promoting Neurological Recovery in the Post-Acute Stroke Phase: Benefits and Challenges

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Promoting neurological recovery in the post-acute stroke phase: benefits and challenges.

BACKGROUND Profound cellular and biochemical remodeling processes occur in the brain following an ischemic stroke, raising the possibility that we may be able to promote neurological recovery by harnessing the brain's endogenous recovery processes with pharmacological or cell-based therapies. There is a compelling body of evidence that cerebral plasticity and neurological recovery can be stimul...

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Acute Phase Reactants as a Prognostic Factor in Acute Stroke

Introduction: Elevated levels of CRP are present among patients at risk for further first-ever myocardial infarction and stroke. It has been shown that after ischemic stroke, increased levels of CRP are associated with unfavorable outcomes. Methods: From 120 patients admitted to the emergency unit of our hospital with the diagnosis of stroke CRP, D-dimer and ferritin level was measured and the ...

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The Impact of Acute Phase Domain-Specific Cognitive Function on Post-stroke Functional Recovery

OBJECTIVE To assess whether the cognitive function in the acute stage evaluated by domain-specific neuropsychological assessments would be an independent predictor of functional outcome after stroke. METHODS Forty patients underwent 4 domain-specific neuropsychological examinations about 3 weeks after the onset of stroke. The tests included the Boston Naming Test (BNT), the construction recal...

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Promoting neurological recovery of function via metaplasticity.

The modification of synapses by neural activity has been proposed to be the substrate for experience-dependent brain development, learning, and recovery of visual function after brain injury. The effectiveness or 'strength' of synaptic transmission can be persistently modified in response to defined patterns of pre- and post-synaptic activity. Well-studied examples of this type of synaptic plas...

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Neurological emergencies: acute stroke.

Stroke causes a vast amount of death and disability throughout the world, yet for many healthcare professionals it remains an area of therapeutic nihilism, and thus uninteresting. This negative perception is shared by the general public, who often have a poor understanding of the early symptoms and significance of a stroke. Yet within the past few years there have been many important developmen...

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ژورنال

عنوان ژورنال: European Neurology

سال: 2014

ISSN: 0014-3022,1421-9913

DOI: 10.1159/000365171